Spider-Man seeks Curt Connors' aid to help reverse the aging effects of the Vulture's talons. Meanwhile, the Vulture sporadically turns into the man-spider from the mutagenics he absorbed with Spider-Man's youth. At the same time, the Scorpion grabs Dr. Farley Stillwell to seek a cure for his own mutation, while Connors is feeling the onset of his reptilian transformation.