Hot Ones is back, and hotter than ever! Season 22 kicks off on Thursday, September 21, at 11am EST with a historic Hot Ones booking. But first, the new lineup of hot sauces that will be scorching out celebrities all season long. There are two exciting new Hot Ones sauces at the table—our first-ever Buffalo sauce, and a brand-new Last Dab—as well as some flavor-packed newcomers.