Five years previously everyone in Ōtsuka village died in a plague, but there were 3 survivors, Shino Inuzuka, Sosuke Inukawa and Hamaji. They took shelter in a church near another village, which happens to be near a dark and dangerous forest. The church, as well as the survivors, are viewed with suspicion by the villagers. Now the Imperial Church comes in search of "Murasame" the demon blade that contains "life" which Shino possesses.