The ultimate failure of Woodrow Wilson destroys himself in his desperate struggle for the League of Nations. The President and the Senate fight for control of American foreign policy: the Senate wins. Wilson is opposed by a powerful coalition of conservatives like Sen. Henry Cabot Lodge, and his case to the people embarks on a grueling 8,000 mile train trip and suffers a stroke. During his illness, Mrs. Wilson acts as regent, or caretaker president for 17 months. Wilson refuses to compromise on the League of Nations and ironically is responsible for its defeat.