Chicago, last week of April 1933. Frank Nitti is offered a huge quantity of Chinese opium. Ever since the government had established the Bureau of Narcotics in 1930, the flow of opium from China to the USA had slowed to a trickle, and by 1932 the flow had almost ceased; now, with the end of Prohibition seeming imminent, the Syndicate is ready to deal in opium again. Late on the night of May 4, Nitti sends one of his top lieutenants, Ed Getty, to pick up some opium from Art Rele and his thug Cliff Anders. But Ness and Lee Hobson show up, too; in the shootout, only Art Rele escapes.