Joining scientist Benton Quest, his plucky son Jonny, bodyguard Race Bannon and Jonny's young pal Hadji are Benton's biologist wife Rachel, Race's ex-wife Jade and young 12-year-old Jessie, who harbors a big secret. Throughout, Team Quest battles the evil schemes of modern-day alchemist Dr. Zin, who has cloned himself and created an army of mutant reptiles in the Peruvian rain forest. The clash there results in a tragedy that changes Jonny's life forever - and later leads to a worldwide pursuit of Zin that includes examining rare Leonardo da Vinci documents in Paris, exploring the Roman catacombs and a final confrontation in the Australian outback.