It's a Never Been Kissed (1999) cast reunion, with guests Molly Shannon, David Arquette and Michael Vartan reuniting with host Drew Barrymore, two decades after the beloved film premiered. Plus, join Drew and RuPaul as they embark on a new journey together and head back to school to get their high school diploma equivalent. Then, in an all-new Wildflower, Drew spotlights women who have paved their own way to success, including a NASA Aerospace Engineer working on the Perseverance Rover, which is currently searching for signs of life on Mars. Plus, Drew is celebrating hometown pride, all week long, with viewers sharing tours of what makes their town so special and unique, including today's hometown spirit tour of Denver.